Details for gene set GOBP_DEFENSE_RESPONSE_TO_GRAM_NEGATIVE

Table: GSEA Results Summary

Dataset	538122_collapsed_to_symbols.538122
Phenotype	538122.cls
Upregulated in class	Resistant
GeneSet	GOBP_DEFENSE_RESPONSE_TO_GRAM_NEGATIVE_BACTERIUM
Enrichment Score (ES)	0.6172914
Normalized Enrichment Score (NES)	2.2108486
Nominal p-value	0.0
FDR q-value	3.3868075E-4
FWER p-Value	0.005

Table: GSEA details [plain text format]
	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	LYZ	lysozyme [Source:HGNC Symbol;Acc:HGNC:6740]	11	0.428	0.0740	Yes
2	DEFA1	defensin alpha 1 [Source:HGNC Symbol;Acc:HGNC:2761]	29	0.370	0.1375	Yes
3	ELANE	elastase, neutrophil expressed [Source:HGNC Symbol;Acc:HGNC:3309]	35	0.364	0.2007	Yes
4	LTF	lactotransferrin [Source:HGNC Symbol;Acc:HGNC:6720]	42	0.349	0.2613	Yes
5	DEFA4	defensin alpha 4 [Source:HGNC Symbol;Acc:HGNC:2763]	44	0.342	0.3211	Yes
6	AZU1	azurocidin 1 [Source:HGNC Symbol;Acc:HGNC:913]	49	0.334	0.3792	Yes
7	CAMP	cathelicidin antimicrobial peptide [Source:HGNC Symbol;Acc:HGNC:1472]	168	0.225	0.4094	Yes
8	BPI	bactericidal permeability increasing protein [Source:HGNC Symbol;Acc:HGNC:1095]	181	0.217	0.4464	Yes
9	TNFRSF14	TNF receptor superfamily member 14 [Source:HGNC Symbol;Acc:HGNC:11912]	239	0.193	0.4758	Yes
10	CTSG	cathepsin G [Source:HGNC Symbol;Acc:HGNC:2532]	286	0.178	0.5034	Yes
11	RNASE2	ribonuclease A family member 2 [Source:HGNC Symbol;Acc:HGNC:10045]	305	0.173	0.5322	Yes
12	SERPINE1	serpin family E member 1 [Source:HGNC Symbol;Acc:HGNC:8583]	429	0.150	0.5489	Yes
13	DROSHA	drosha ribonuclease III [Source:HGNC Symbol;Acc:HGNC:17904]	507	0.139	0.5672	Yes
14	PYCARD	PYD and CARD domain containing [Source:HGNC Symbol;Acc:HGNC:16608]	708	0.119	0.5725	Yes
15	OPTN	optineurin [Source:HGNC Symbol;Acc:HGNC:17142]	732	0.117	0.5913	Yes
16	GSDMD	gasdermin D [Source:HGNC Symbol;Acc:HGNC:25697]	786	0.113	0.6068	Yes
17	IL6	interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018]	1019	0.100	0.6062	Yes
18	NOS2	nitric oxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:7873]	1255	0.089	0.6035	Yes
19	MR1	major histocompatibility complex, class I-related [Source:HGNC Symbol;Acc:HGNC:4975]	1649	0.077	0.5864	Yes
20	AQP1	aquaporin 1 (Colton blood group) [Source:HGNC Symbol;Acc:HGNC:633]	1662	0.076	0.5988	Yes
21	IL6R	interleukin 6 receptor [Source:HGNC Symbol;Acc:HGNC:6019]	1800	0.073	0.6008	Yes
22	RNASE3	ribonuclease A family member 3 [Source:HGNC Symbol;Acc:HGNC:10046]	1904	0.070	0.6051	Yes
23	DMBT1	deleted in malignant brain tumors 1 [Source:HGNC Symbol;Acc:HGNC:2926]	2151	0.064	0.5972	Yes
24	TREM1	triggering receptor expressed on myeloid cells 1 [Source:HGNC Symbol;Acc:HGNC:17760]	2153	0.064	0.6084	Yes
25	DEFA6	defensin alpha 6 [Source:HGNC Symbol;Acc:HGNC:2765]	2183	0.064	0.6173	Yes
26	DEFB126	defensin beta 126 [Source:HGNC Symbol;Acc:HGNC:15900]	2432	0.058	0.6082	No
27	ADGRB1	adhesion G protein-coupled receptor B1 [Source:HGNC Symbol;Acc:HGNC:943]	3465	0.041	0.5351	No
28	CHGA	chromogranin A [Source:HGNC Symbol;Acc:HGNC:1929]	3783	0.037	0.5169	No
29	SELP	selectin P [Source:HGNC Symbol;Acc:HGNC:10721]	3824	0.036	0.5201	No
30	CD160	CD160 molecule [Source:HGNC Symbol;Acc:HGNC:17013]	3998	0.034	0.5126	No
31	CXCL6	C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643]	4322	0.030	0.4926	No
32	IL17A	interleukin 17A [Source:HGNC Symbol;Acc:HGNC:5981]	4810	0.024	0.4588	No
33	SLC11A1	solute carrier family 11 member 1 [Source:HGNC Symbol;Acc:HGNC:10907]	4947	0.022	0.4521	No
34	IL23A	interleukin 23 subunit alpha [Source:HGNC Symbol;Acc:HGNC:15488]	5115	0.020	0.4427	No
35	RARRES2	retinoic acid receptor responder 2 [Source:HGNC Symbol;Acc:HGNC:9868]	5255	0.019	0.4351	No
36	CD4	CD4 molecule [Source:HGNC Symbol;Acc:HGNC:1678]	5668	0.014	0.4055	No
37	F2RL1	F2R like trypsin receptor 1 [Source:HGNC Symbol;Acc:HGNC:3538]	5847	0.012	0.3937	No
38	DEFB1	defensin beta 1 [Source:HGNC Symbol;Acc:HGNC:2766]	6365	0.005	0.3544	No
39	UMOD	uromodulin [Source:HGNC Symbol;Acc:HGNC:12559]	6447	0.005	0.3489	No
40	LBP	lipopolysaccharide binding protein [Source:HGNC Symbol;Acc:HGNC:6517]	6537	0.004	0.3426	No
41	DEFA5	defensin alpha 5 [Source:HGNC Symbol;Acc:HGNC:2764]	7216	-0.004	0.2906	No
42	DEFB4A	defensin beta 4A [Source:HGNC Symbol;Acc:HGNC:2767]	7229	-0.004	0.2904	No
43	IL22RA1	interleukin 22 receptor subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:13700]	7265	-0.005	0.2885	No
44	RPS19	ribosomal protein S19 [Source:HGNC Symbol;Acc:HGNC:10402]	7283	-0.005	0.2880	No
45	RPL30	ribosomal protein L30 [Source:HGNC Symbol;Acc:HGNC:10333]	7306	-0.005	0.2872	No
46	S100A7	S100 calcium binding protein A7 [Source:HGNC Symbol;Acc:HGNC:10497]	7397	-0.006	0.2812	No
47	PRB3	proline rich protein BstNI subfamily 3 [Source:HGNC Symbol;Acc:HGNC:9339]	7643	-0.009	0.2638	No
48	PRKD1	protein kinase D1 [Source:HGNC Symbol;Acc:HGNC:9407]	8210	-0.017	0.2226	No
49	TLR4	toll like receptor 4 [Source:HGNC Symbol;Acc:HGNC:11850]	8774	-0.024	0.1831	No
50	FCN2	ficolin 2 [Source:HGNC Symbol;Acc:HGNC:3624]	9342	-0.033	0.1447	No
51	TREM2	triggering receptor expressed on myeloid cells 2 [Source:HGNC Symbol;Acc:HGNC:17761]	9469	-0.035	0.1410	No
52	F2	coagulation factor II, thrombin [Source:HGNC Symbol;Acc:HGNC:3535]	10003	-0.045	0.1073	No
53	IL12B	interleukin 12B [Source:HGNC Symbol;Acc:HGNC:5970]	10613	-0.059	0.0703	No
54	RNASE6	ribonuclease A family member k6 [Source:HGNC Symbol;Acc:HGNC:10048]	10899	-0.067	0.0599	No
55	TUSC2	tumor suppressor 2, mitochondrial calcium regulator [Source:HGNC Symbol;Acc:HGNC:17034]	10953	-0.069	0.0679	No
56	HMGB2	high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000]	12641	-0.188	-0.0305	No
57	IGHM	immunoglobulin heavy constant mu [Source:HGNC Symbol;Acc:HGNC:5541]	12842	-0.291	0.0049	No