Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | brain2_tissuebrain_collapsed_to_symbols.Brain_tissue_TIRRKO_vs_Brain_control.cls #Brain_tissue_TIRRKO_versus_Brain_control.Brain_tissue_TIRRKO_vs_Brain_control.cls #Brain_tissue_TIRRKO_versus_Brain_control_repos |
| Phenotype | Brain_tissue_TIRRKO_vs_Brain_control.cls#Brain_tissue_TIRRKO_versus_Brain_control_repos |
| Upregulated in class | Brain_control |
| GeneSet | KEGG_ECM_RECEPTOR_INTERACTION |
| Enrichment Score (ES) | -0.31089613 |
| Normalized Enrichment Score (NES) | -1.0049635 |
| Nominal p-value | 0.48970747 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | LAMA4 | laminin subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:6484] | 74 | 0.864 | 0.0316 | No |
| 2 | ITGB7 | integrin subunit beta 7 [Source:HGNC Symbol;Acc:HGNC:6162] | 200 | 0.645 | 0.0514 | No |
| 3 | SDC1 | syndecan 1 [Source:HGNC Symbol;Acc:HGNC:10658] | 220 | 0.626 | 0.0762 | No |
| 4 | GP5 | glycoprotein V platelet [Source:HGNC Symbol;Acc:HGNC:4443] | 255 | 0.598 | 0.0991 | No |
| 5 | CD36 | CD36 molecule [Source:HGNC Symbol;Acc:HGNC:1663] | 409 | 0.514 | 0.1118 | No |
| 6 | GP9 | glycoprotein IX platelet [Source:HGNC Symbol;Acc:HGNC:4444] | 651 | 0.424 | 0.1159 | No |
| 7 | GP1BB | glycoprotein Ib platelet subunit beta [Source:HGNC Symbol;Acc:HGNC:4440] | 779 | 0.382 | 0.1246 | No |
| 8 | COL5A2 | collagen type V alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2210] | 948 | 0.339 | 0.1293 | No |
| 9 | COL3A1 | collagen type III alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2201] | 992 | 0.328 | 0.1405 | No |
| 10 | COL2A1 | collagen type II alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2200] | 1014 | 0.323 | 0.1527 | No |
| 11 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 1038 | 0.318 | 0.1646 | No |
| 12 | COL1A1 | collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197] | 1182 | 0.294 | 0.1688 | No |
| 13 | ITGA5 | integrin subunit alpha 5 [Source:HGNC Symbol;Acc:HGNC:6141] | 1218 | 0.287 | 0.1787 | No |
| 14 | SPP1 | secreted phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:11255] | 1224 | 0.286 | 0.1902 | No |
| 15 | FN1 | fibronectin 1 [Source:HGNC Symbol;Acc:HGNC:3778] | 1243 | 0.282 | 0.2009 | No |
| 16 | VWF | von Willebrand factor [Source:HGNC Symbol;Acc:HGNC:12726] | 1383 | 0.258 | 0.2038 | No |
| 17 | LAMB1 | laminin subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:6486] | 1669 | 0.215 | 0.1968 | No |
| 18 | COL5A3 | collagen type V alpha 3 chain [Source:HGNC Symbol;Acc:HGNC:14864] | 1761 | 0.206 | 0.2003 | No |
| 19 | THBS1 | thrombospondin 1 [Source:HGNC Symbol;Acc:HGNC:11785] | 1883 | 0.191 | 0.2014 | No |
| 20 | GP1BA | glycoprotein Ib platelet subunit alpha [Source:HGNC Symbol;Acc:HGNC:4439] | 2074 | 0.173 | 0.1980 | No |
| 21 | COL5A1 | collagen type V alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2209] | 2426 | 0.147 | 0.1845 | No |
| 22 | LAMC1 | laminin subunit gamma 1 [Source:HGNC Symbol;Acc:HGNC:6492] | 2613 | 0.132 | 0.1796 | No |
| 23 | LAMC2 | laminin subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:6493] | 2703 | 0.126 | 0.1799 | No |
| 24 | ITGB4 | integrin subunit beta 4 [Source:HGNC Symbol;Acc:HGNC:6158] | 2920 | 0.111 | 0.1724 | No |
| 25 | ITGAV | integrin subunit alpha V [Source:HGNC Symbol;Acc:HGNC:6150] | 3423 | 0.082 | 0.1479 | No |
| 26 | ITGA9 | integrin subunit alpha 9 [Source:HGNC Symbol;Acc:HGNC:6145] | 3471 | 0.080 | 0.1485 | No |
| 27 | ITGB6 | integrin subunit beta 6 [Source:HGNC Symbol;Acc:HGNC:6161] | 3613 | 0.072 | 0.1436 | No |
| 28 | HSPG2 | heparan sulfate proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:5273] | 3639 | 0.071 | 0.1452 | No |
| 29 | COL4A4 | collagen type IV alpha 4 chain [Source:HGNC Symbol;Acc:HGNC:2206] | 3757 | 0.065 | 0.1413 | No |
| 30 | SDC4 | syndecan 4 [Source:HGNC Symbol;Acc:HGNC:10661] | 4159 | 0.046 | 0.1209 | No |
| 31 | GP6 | glycoprotein VI platelet [Source:HGNC Symbol;Acc:HGNC:14388] | 4920 | 0.011 | 0.0790 | No |
| 32 | ITGB5 | integrin subunit beta 5 [Source:HGNC Symbol;Acc:HGNC:6160] | 5037 | 0.006 | 0.0728 | No |
| 33 | SDC2 | syndecan 2 [Source:HGNC Symbol;Acc:HGNC:10659] | 5080 | 0.005 | 0.0706 | No |
| 34 | CD47 | CD47 molecule [Source:HGNC Symbol;Acc:HGNC:1682] | 6032 | -0.002 | 0.0178 | No |
| 35 | ITGB8 | integrin subunit beta 8 [Source:HGNC Symbol;Acc:HGNC:6163] | 6530 | -0.018 | -0.0092 | No |
| 36 | ITGA1 | integrin subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:6134] | 6698 | -0.023 | -0.0176 | No |
| 37 | ITGB3 | integrin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6156] | 6990 | -0.032 | -0.0325 | No |
| 38 | SV2B | synaptic vesicle glycoprotein 2B [Source:HGNC Symbol;Acc:HGNC:16874] | 7566 | -0.048 | -0.0625 | No |
| 39 | ITGA6 | integrin subunit alpha 6 [Source:HGNC Symbol;Acc:HGNC:6142] | 7841 | -0.056 | -0.0755 | No |
| 40 | VTN | vitronectin [Source:HGNC Symbol;Acc:HGNC:12724] | 7882 | -0.057 | -0.0753 | No |
| 41 | COL1A2 | collagen type I alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2198] | 8276 | -0.068 | -0.0944 | No |
| 42 | DAG1 | dystroglycan 1 [Source:HGNC Symbol;Acc:HGNC:2666] | 8284 | -0.069 | -0.0920 | No |
| 43 | COL4A1 | collagen type IV alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2202] | 8910 | -0.086 | -0.1232 | No |
| 44 | COL6A2 | collagen type VI alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2212] | 9135 | -0.092 | -0.1319 | No |
| 45 | COMP | cartilage oligomeric matrix protein [Source:HGNC Symbol;Acc:HGNC:2227] | 9550 | -0.105 | -0.1506 | No |
| 46 | SV2A | synaptic vesicle glycoprotein 2A [Source:HGNC Symbol;Acc:HGNC:20566] | 9753 | -0.110 | -0.1573 | No |
| 47 | SDC3 | syndecan 3 [Source:HGNC Symbol;Acc:HGNC:10660] | 10078 | -0.120 | -0.1704 | No |
| 48 | SV2C | synaptic vesicle glycoprotein 2C [Source:HGNC Symbol;Acc:HGNC:30670] | 10655 | -0.136 | -0.1968 | No |
| 49 | ITGB1 | integrin subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:6153] | 11146 | -0.151 | -0.2179 | No |
| 50 | TNC | tenascin C [Source:HGNC Symbol;Acc:HGNC:5318] | 11346 | -0.157 | -0.2225 | No |
| 51 | TNR | tenascin R [Source:HGNC Symbol;Acc:HGNC:11953] | 11713 | -0.169 | -0.2359 | No |
| 52 | LAMA5 | laminin subunit alpha 5 [Source:HGNC Symbol;Acc:HGNC:6485] | 12090 | -0.182 | -0.2493 | No |
| 53 | COL6A1 | collagen type VI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2211] | 12987 | -0.215 | -0.2903 | No |
| 54 | ITGA3 | integrin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6139] | 13083 | -0.219 | -0.2865 | No |
| 55 | COL4A2 | collagen type IV alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2203] | 13113 | -0.221 | -0.2790 | No |
| 56 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 13239 | -0.225 | -0.2766 | No |
| 57 | LAMB3 | laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490] | 13279 | -0.227 | -0.2694 | No |
| 58 | LAMA2 | laminin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6482] | 13419 | -0.233 | -0.2675 | No |
| 59 | CHAD | chondroadherin [Source:HGNC Symbol;Acc:HGNC:1909] | 13555 | -0.239 | -0.2651 | No |
| 60 | COL6A6 | collagen type VI alpha 6 chain [Source:HGNC Symbol;Acc:HGNC:27023] | 13622 | -0.243 | -0.2588 | No |
| 61 | AGRN | agrin [Source:HGNC Symbol;Acc:HGNC:329] | 14169 | -0.272 | -0.2779 | No |
| 62 | RELN | reelin [Source:HGNC Symbol;Acc:HGNC:9957] | 14333 | -0.280 | -0.2754 | No |
| 63 | LAMB2 | laminin subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:6487] | 14439 | -0.286 | -0.2695 | No |
| 64 | COL4A6 | collagen type IV alpha 6 chain [Source:HGNC Symbol;Acc:HGNC:2208] | 14667 | -0.298 | -0.2698 | No |
| 65 | ITGA2 | integrin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6137] | 15406 | -0.348 | -0.2965 | Yes |
| 66 | TNXB | tenascin XB [Source:HGNC Symbol;Acc:HGNC:11976] | 15485 | -0.355 | -0.2861 | Yes |
| 67 | ITGA7 | integrin subunit alpha 7 [Source:HGNC Symbol;Acc:HGNC:6143] | 15493 | -0.356 | -0.2718 | Yes |
| 68 | THBS3 | thrombospondin 3 [Source:HGNC Symbol;Acc:HGNC:11787] | 15722 | -0.373 | -0.2690 | Yes |
| 69 | COL11A2 | collagen type XI alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2187] | 15854 | -0.383 | -0.2605 | Yes |
| 70 | ITGA4 | integrin subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:6140] | 15927 | -0.389 | -0.2484 | Yes |
| 71 | TNN | tenascin N [Source:HGNC Symbol;Acc:HGNC:22942] | 16432 | -0.440 | -0.2582 | Yes |
| 72 | LAMA3 | laminin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6483] | 16748 | -0.487 | -0.2556 | Yes |
| 73 | THBS4 | thrombospondin 4 [Source:HGNC Symbol;Acc:HGNC:11788] | 16987 | -0.531 | -0.2469 | Yes |
| 74 | ITGA2B | integrin subunit alpha 2b [Source:HGNC Symbol;Acc:HGNC:6138] | 17260 | -0.595 | -0.2375 | Yes |
| 75 | ITGA11 | integrin subunit alpha 11 [Source:HGNC Symbol;Acc:HGNC:6136] | 17301 | -0.608 | -0.2145 | Yes |
| 76 | LAMA1 | laminin subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:6481] | 17329 | -0.616 | -0.1905 | Yes |
| 77 | THBS2 | thrombospondin 2 [Source:HGNC Symbol;Acc:HGNC:11786] | 17397 | -0.638 | -0.1679 | Yes |
| 78 | COL6A3 | collagen type VI alpha 3 chain [Source:HGNC Symbol;Acc:HGNC:2213] | 17501 | -0.677 | -0.1456 | Yes |
| 79 | IBSP | integrin binding sialoprotein [Source:HGNC Symbol;Acc:HGNC:5341] | 17553 | -0.700 | -0.1195 | Yes |
| 80 | COL11A1 | collagen type XI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2186] | 17758 | -0.807 | -0.0975 | Yes |
| 81 | LAMC3 | laminin subunit gamma 3 [Source:HGNC Symbol;Acc:HGNC:6494] | 17793 | -0.850 | -0.0642 | Yes |
| 82 | ITGA8 | integrin subunit alpha 8 [Source:HGNC Symbol;Acc:HGNC:6144] | 17866 | -0.928 | -0.0298 | Yes |
| 83 | ITGA10 | integrin subunit alpha 10 [Source:HGNC Symbol;Acc:HGNC:6135] | 17872 | -0.938 | 0.0087 | Yes |
