Details for gene set KEGG_GNRH_SIGNALING

Table: GSEA Results Summary

Dataset	TIRR_p53KO_dKO_PGAT.P53KO_TIRRWT_PGAT_vs_P53KO_TIRRKO_PGAT.cls #P53KO_TIRRKO_PGAT_versus_P53KO_TIRRWT_PGAT
Phenotype	P53KO_TIRRWT_PGAT_vs_P53KO_TIRRKO_PGAT.cls#P53KO_TIRRKO_PGAT_versus_P53KO_TIRRWT_PGAT
Upregulated in class	P53KO_TIRRWT_PGAT
GeneSet	KEGG_GNRH_SIGNALING_PATHWAY
Enrichment Score (ES)	-0.3338887
Normalized Enrichment Score (NES)	-1.3330262
Nominal p-value	0.05541237
FDR q-value	0.19052155
FWER p-Value	1.0

Table: GSEA details [plain text format]
	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	MAP3K2	n/a	90	0.717	0.0269	No
2	PLCB1	n/a	264	0.562	0.0408	No
3	PRKACA	n/a	762	0.426	0.0257	No
4	CALML3	n/a	1324	0.358	0.0030	No
5	PLA2G12A	n/a	1342	0.357	0.0183	No
6	GNRHR	n/a	1440	0.347	0.0276	No
7	PLA2G2E	n/a	1471	0.344	0.0415	No
8	ADCY8	n/a	1826	0.314	0.0312	No
9	SOS1	n/a	2430	0.273	0.0016	No
10	MMP2	n/a	2581	0.264	0.0033	No
11	CALM3	n/a	2623	0.262	0.0126	No
12	PLA2G5	n/a	2942	0.245	0.0017	No
13	SOS2	n/a	3044	0.240	0.0057	No
14	GNAS	n/a	3377	0.221	-0.0073	No
15	MAPK13	n/a	3465	0.217	-0.0033	No
16	RAF1	n/a	3489	0.216	0.0050	No
17	ADCY5	n/a	3525	0.213	0.0125	No
18	PLD1	n/a	3534	0.213	0.0218	No
19	MAPK9	n/a	3569	0.211	0.0291	No
20	CAMK2D	n/a	3813	0.199	0.0213	No
21	MAPK14	n/a	4137	0.183	0.0072	No
22	MAP2K6	n/a	4532	0.163	-0.0129	No
23	PLA2G4A	n/a	4766	0.152	-0.0222	No
24	SRC	n/a	4839	0.149	-0.0203	No
25	MAP3K4	n/a	5039	0.138	-0.0278	No
26	ADCY9	n/a	5310	0.125	-0.0410	No
27	CACNA1F	n/a	5428	0.119	-0.0437	No
28	EGFR	n/a	5637	0.108	-0.0532	No
29	PRKACB	n/a	5780	0.102	-0.0585	No
30	MAP2K2	n/a	5902	0.095	-0.0626	No
31	CDC42	n/a	6058	0.087	-0.0694	No
32	MAPK3	n/a	6086	0.085	-0.0673	No
33	ELK1	n/a	6138	0.083	-0.0671	No
34	MAP2K1	n/a	6647	0.055	-0.1001	No
35	PRKCA	n/a	6670	0.054	-0.0992	No
36	CALM1	n/a	6892	0.043	-0.1127	No
37	MAP2K3	n/a	6969	0.039	-0.1162	No
38	ADCY6	n/a	6991	0.038	-0.1159	No
39	PTK2B	n/a	7071	0.034	-0.1199	No
40	MAPK8	n/a	7244	0.025	-0.1308	No
41	ADCY2	n/a	7258	0.024	-0.1306	No
42	GNAQ	n/a	7281	0.023	-0.1310	No
43	PLA2G6	n/a	7346	0.020	-0.1346	No
44	MAP2K4	n/a	7431	0.015	-0.1398	No
45	GRB2	n/a	7583	0.008	-0.1500	No
46	CALM2	n/a	7776	-0.002	-0.1633	No
47	GNA11	n/a	7859	-0.007	-0.1687	No
48	PLCB3	n/a	8032	-0.017	-0.1800	No
49	CACNA1D	n/a	8067	-0.019	-0.1815	No
50	HRAS	n/a	8110	-0.022	-0.1834	No
51	MAPK1	n/a	8171	-0.026	-0.1864	No
52	CAMK2B	n/a	8992	-0.077	-0.2403	No
53	MAP2K7	n/a	9222	-0.093	-0.2520	No
54	ITPR2	n/a	9256	-0.095	-0.2499	No
55	NRAS	n/a	9823	-0.132	-0.2835	No
56	ADCY1	n/a	9954	-0.142	-0.2860	No
57	PLD2	n/a	10284	-0.166	-0.3014	No
58	ADCY3	n/a	10687	-0.197	-0.3204	No
59	KRAS	n/a	10707	-0.198	-0.3126	No
60	ITPR3	n/a	11012	-0.223	-0.3235	Yes
61	MAP3K3	n/a	11025	-0.225	-0.3140	Yes
62	MAP3K1	n/a	11131	-0.235	-0.3105	Yes
63	ITPR1	n/a	11271	-0.249	-0.3087	Yes
64	PLA2G4E	n/a	11298	-0.252	-0.2988	Yes
65	ATF4	n/a	11595	-0.283	-0.3065	Yes
66	MMP14	n/a	11782	-0.306	-0.3054	Yes
67	JUN	n/a	11816	-0.309	-0.2934	Yes
68	PLA2G3	n/a	11929	-0.323	-0.2862	Yes
69	CAMK2G	n/a	11982	-0.330	-0.2746	Yes
70	PLA2G2D	n/a	12360	-0.380	-0.2835	Yes
71	PRKCB	n/a	12453	-0.389	-0.2719	Yes
72	CAMK2A	n/a	12617	-0.411	-0.2643	Yes
73	ADCY7	n/a	12702	-0.423	-0.2506	Yes
74	PRKX	n/a	12737	-0.427	-0.2332	Yes
75	PLCB4	n/a	12824	-0.436	-0.2190	Yes
76	CACNA1S	n/a	12856	-0.441	-0.2008	Yes
77	PLCB2	n/a	13259	-0.505	-0.2055	Yes
78	PRKCD	n/a	13350	-0.523	-0.1876	Yes
79	CACNA1C	n/a	13457	-0.547	-0.1697	Yes
80	MAPK7	n/a	13508	-0.559	-0.1473	Yes
81	GNRH1	n/a	13819	-0.659	-0.1385	Yes
82	MAPK12	n/a	14107	-0.819	-0.1207	Yes
83	MAPK11	n/a	14177	-0.870	-0.0852	Yes
84	ADCY4	n/a	14236	-0.939	-0.0457	Yes
85	HBEGF	n/a	14331	-1.165	0.0016	Yes