Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
The same image in compressed SVG format
| Dataset | TIRRdKO_KO_PGAT.TIRR_KO_PGAT_vs_P53KO_TIRRKO_PGAT.cls #TIRR_KO_PGAT_versus_P53KO_TIRRKO_PGAT |
| Phenotype | TIRR_KO_PGAT_vs_P53KO_TIRRKO_PGAT.cls#TIRR_KO_PGAT_versus_P53KO_TIRRKO_PGAT |
| Upregulated in class | P53KO_TIRRKO_PGAT |
| GeneSet | KEGG_COMPLEMENT_AND_COAGULATION_CASCADES |
| Enrichment Score (ES) | -0.42733926 |
| Normalized Enrichment Score (NES) | -1.5318712 |
| Nominal p-value | 0.018387552 |
| FDR q-value | 0.109804995 |
| FWER p-Value | 0.918 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | C6 | n/a | 24 | 1.417 | 0.0651 | No |
| 2 | CFD | n/a | 714 | 0.631 | 0.0467 | No |
| 3 | SERPINE1 | n/a | 795 | 0.609 | 0.0697 | No |
| 4 | MASP1 | n/a | 1248 | 0.497 | 0.0616 | No |
| 5 | C2 | n/a | 1660 | 0.428 | 0.0530 | No |
| 6 | CR2 | n/a | 2003 | 0.383 | 0.0472 | No |
| 7 | CFH | n/a | 2307 | 0.351 | 0.0425 | No |
| 8 | C8G | n/a | 3128 | 0.268 | -0.0022 | No |
| 9 | VWF | n/a | 3670 | 0.224 | -0.0295 | No |
| 10 | KLKB1 | n/a | 3885 | 0.207 | -0.0347 | No |
| 11 | KNG1 | n/a | 4002 | 0.198 | -0.0335 | No |
| 12 | C3 | n/a | 4107 | 0.189 | -0.0318 | No |
| 13 | BDKRB2 | n/a | 4480 | 0.163 | -0.0501 | No |
| 14 | PLAUR | n/a | 4508 | 0.161 | -0.0444 | No |
| 15 | MASP2 | n/a | 4516 | 0.160 | -0.0374 | No |
| 16 | SERPINC1 | n/a | 4827 | 0.138 | -0.0525 | No |
| 17 | TFPI | n/a | 5159 | 0.114 | -0.0703 | No |
| 18 | CD46 | n/a | 6364 | 0.032 | -0.1529 | No |
| 19 | C7 | n/a | 6719 | 0.008 | -0.1773 | No |
| 20 | PLAU | n/a | 7388 | -0.037 | -0.2222 | No |
| 21 | C1R | n/a | 8215 | -0.095 | -0.2755 | No |
| 22 | SERPINA1 | n/a | 8394 | -0.109 | -0.2828 | No |
| 23 | CR1 | n/a | 8730 | -0.134 | -0.2999 | No |
| 24 | SERPIND1 | n/a | 9206 | -0.171 | -0.3251 | No |
| 25 | F5 | n/a | 9674 | -0.210 | -0.3478 | No |
| 26 | CD59 | n/a | 10056 | -0.244 | -0.3629 | No |
| 27 | F3 | n/a | 10700 | -0.293 | -0.3941 | No |
| 28 | BDKRB1 | n/a | 11177 | -0.338 | -0.4114 | Yes |
| 29 | PROS1 | n/a | 11189 | -0.339 | -0.3962 | Yes |
| 30 | PROC | n/a | 11267 | -0.346 | -0.3853 | Yes |
| 31 | CFI | n/a | 11477 | -0.368 | -0.3826 | Yes |
| 32 | C5AR1 | n/a | 11684 | -0.391 | -0.3786 | Yes |
| 33 | CD55 | n/a | 11923 | -0.420 | -0.3754 | Yes |
| 34 | F2R | n/a | 12282 | -0.470 | -0.3783 | Yes |
| 35 | C1S | n/a | 12795 | -0.562 | -0.3876 | Yes |
| 36 | F7 | n/a | 12808 | -0.564 | -0.3619 | Yes |
| 37 | F8 | n/a | 12813 | -0.565 | -0.3355 | Yes |
| 38 | F13A1 | n/a | 13128 | -0.637 | -0.3275 | Yes |
| 39 | C4B | n/a | 13162 | -0.645 | -0.2994 | Yes |
| 40 | PLAT | n/a | 13286 | -0.672 | -0.2764 | Yes |
| 41 | F10 | n/a | 13339 | -0.682 | -0.2479 | Yes |
| 42 | C1QA | n/a | 13663 | -0.773 | -0.2340 | Yes |
| 43 | C1QB | n/a | 13702 | -0.784 | -0.1997 | Yes |
| 44 | SERPING1 | n/a | 13770 | -0.807 | -0.1664 | Yes |
| 45 | C4A | n/a | 13839 | -0.835 | -0.1318 | Yes |
| 46 | CFB | n/a | 13843 | -0.839 | -0.0925 | Yes |
| 47 | THBD | n/a | 13879 | -0.856 | -0.0546 | Yes |
| 48 | C1QC | n/a | 13896 | -0.864 | -0.0150 | Yes |
| 49 | C3AR1 | n/a | 14106 | -0.997 | 0.0173 | Yes |
