Project

The non-commercial clinical trial BOOSTER has received a funding recommendation from ABM!

We are delighted to inform you that the clinical research project led by Dr Anna Matyjek, a nephrology specialist from our team, titled “B cell depletion therapy to improve outcomes of steroid-sensitive nephrotic syndrome in adults – the BOOSTER trial,” has received funding recommendation in the second edition of the Medical Research Agency’s Head-to-Head Research […]

The Gray Foundation Grant – next international project in our Department!

Breast cancer is the most common cancer in women. In 2020, 2.3 million new cases were diagnosed, accounting for 11.7% of new cancer diagnoses worldwide. Approximately 5% – 10% of cases involve hereditary breast and ovarian cancer (HBOC), most commonly linked to mutations in the BRCA1 or BRCA2 genes. Currently, BRCA1/2 genetic tests are recommended […]

NCN Grant awarded to Dr. Monika Anna Golińska for endometriosis and ovarian cancer research.

We are excited to share that Dr. Monika Anna Golińska has been awarded the NCN “MSCA POLONEZ BIS 3” grant for her project titled “ENDOVO: Identifying biomarkers in endometriosis-associated ovarian cancer using photoacoustic imaging and data mining.” The project will be conducted at the Department of Biostatistics and Translational Medicine. Endometriosis is a condition where […]

Importance of the NUDT16L1-TP53BP1-TP53 axis in obesity and type 2 diabetes

Obesity is one of the main risk factors for the development of type 2 diabetes as it leads to excessive production of free radicals, disruptions in glucose and fatty acid metabolism, and insulin resistance. The study focuses on understanding the role of the NUDT16L1 protein, which is a key regulator of TP53 activity. Deletion or […]

Decoding “metabolic memory” – how do glycemic control and variability affect epigenetic changes in young people with type 1 diabetes?

Type 1 diabetes (T1D) is the most common metabolic disease in childhood. It is caused by the destruction of pancreatic beta cells by one’s malfunctioning immune system. The lost beta cells are responsible for the production of insulin – an essential hormone in blood glucose levels regulation. Treatment of T1D demands life-long subcutaneous insulin supplementation […]

Screening for mobilization failure during hematopoietic stem cell transplantation through non-coding RNA profiling.

Transplantation of hematopoietic stem cells from bone marrow is a widely used method for treating various diseases, such as blood cancers, metabolic disorders, and autoimmune diseases. However, some patients are unable to undergo this procedure effectively due to problems with mobilizing an adequate number of stem cells. The study proposes to evaluate the role of […]

The role of proinsulin C-peptide and G-protein coupled receptor 146 (GPR146) – clinical observation of their signaling pathway’s impact on molecular pathways involved in diabetes-related complications.

The project aims to investigate the role of proinsulin C-peptide and G-protein coupled receptor 146 (GPR146) in type 2 diabetes mellitus (T2DM) complications. C-peptide is a short peptide that influences multiple cellular pathways, and its role in diabetes complications has become increasingly evident. The study postulates that C-peptide interacts with the GPR146 receptor, which may […]

Intrinsic tumour radiosensitivity as a marker of chemoradiotherapy-induced immunogenic effects in rectal cancer

Colorectal cancer (CRC) is the second leading cause of cancer death in the world. Standard treatment of patients with locally advanced cancer of the rectum includes chemoradiotherapy (CHRT) before surgery. In recent years, the new standard of treatment for some patients with CRC has become immunotherapy with the use of so-called immune checkpoint inhibitors (ICI) […]

Bob Bast’s Translational Research Grant 2022

We are happy to announce that our team, as the part of international collaboration with UK FOCSS and Dana Farber Cancer Institute, was awarded the 2022 Bob Bast’s Translational Research Grant for the project entitled “Blood-based screening for identification and monitoring of women at elevated risk for breast and ovarian cancer”. The grant has been […]

Two projects awarded Polish Diabetes Association research grants

We are pleased to announce that the members of our team – Arkadiusz Michalak (PhD student at the Department of Pediatrics, Diabetology, Endocrinology and Nephrology) and Aleksandra Ryk (PhD student at the Department of Biostatistics and Translational Medicine) were among the winners of the competition for research grants of the Polish Diabetes Association. Both PhD […]

Scroll to top