Project

Screening for mobilization failure during hematopoietic stem cell transplantation through non-coding RNA profiling.

Transplantation of hematopoietic stem cells from bone marrow is a widely used method for treating various diseases, such as blood cancers, metabolic disorders, and autoimmune diseases. However, some patients are unable to undergo this procedure effectively due to problems with mobilizing an adequate number of stem cells. The study proposes to evaluate the role of […]

The role of proinsulin C-peptide and G-protein coupled receptor 146 (GPR146) – clinical observation of their signaling pathway’s impact on molecular pathways involved in diabetes-related complications.

The project aims to investigate the role of proinsulin C-peptide and G-protein coupled receptor 146 (GPR146) in type 2 diabetes mellitus (T2DM) complications. C-peptide is a short peptide that influences multiple cellular pathways, and its role in diabetes complications has become increasingly evident. The study postulates that C-peptide interacts with the GPR146 receptor, which may […]

Intrinsic tumour radiosensitivity as a marker of chemoradiotherapy-induced immunogenic effects in rectal cancer

Colorectal cancer (CRC) is the second leading cause of cancer death in the world. Standard treatment of patients with locally advanced cancer of the rectum includes chemoradiotherapy (CHRT) before surgery. In recent years, the new standard of treatment for some patients with CRC has become immunotherapy with the use of so-called immune checkpoint inhibitors (ICI) […]

Bob Bast’s Translational Research Grant 2022

We are happy to announce that our team, as the part of international collaboration with UK FOCSS and Dana Farber Cancer Institute, was awarded the 2022 Bob Bast’s Translational Research Grant for the project entitled “Blood-based screening for identification and monitoring of women at elevated risk for breast and ovarian cancer”. The grant has been […]

Two projects awarded Polish Diabetes Association research grants

We are pleased to announce that the members of our team – Arkadiusz Michalak (PhD student at the Department of Pediatrics, Diabetology, Endocrinology and Nephrology) and Aleksandra Ryk (PhD student at the Department of Biostatistics and Translational Medicine) were among the winners of the competition for research grants of the Polish Diabetes Association. Both PhD […]

We will learn about immune contexture changes induced in lung cancers by chemo- and radiotherapy

Zuzanna Nowicka, a graduate of the Faculty of Medicine at the Medical University of Lodz (2020) and our Individual Course of Study student, was selected in the competition for a doctoral student for the project “Comprehensive characterization of changes in the immune context of a tumor induced by cytotoxic drugs in non-small cell lung cancer” […]

Radiomic methods in cancer research – research visit

We are happy to announce that Urszula Smyczyńska, PhD, MEng, has been awarded a research grant within MINIATURA 5 NCN call. The funds obtained will allow for 10-week research and training stay at Dana-Farber Cancer Institute and Harvard Medical School, Boston, USA, during which our team member will investigate advanced image analysis techniques and their […]

Our team will support DisCoVeRy clinical trial within the POLCRIN research network

The overall objective of this 5-year project is to build a multinational, adaptive European COVID-19 and emerging infectious diseases trial network, based on existing initiatives, experience and expertise, allowing European expansion of DisCoVeRy (WP1) and the establishment of a COVID19 adaptive platform trial (WP2). The DisCoVeRy trial, designed as a multi-arm adaptive repurposing trial, initiated […]

Multiomic analysis of serum and exosomal biomolecules associated with total body irradiation

Wojciech Fendler, MD, PhD, Associate Professor carries out a project financed by a grant from the “OPUS 17” competition of the National Science Center. The human body exposed to high doses of radiation irreversibly loses the ability to produce circulating blood cells, which in a short time leads to death. This is due to multi-profile […]

Scroll to top