Author : Jędrzej Chrzanowski

Success of our students at Juvenes Pro Medicina 2023

For the past few days, our students took part in the Juvenes Pro Medicina conference. Our department was represented by: 1. Mateusz Łaszczych – “Dosimetric predictors of the severity of lymphocyte depletion among patients undergoing radical radiotherapy for non-small cell lung cancer” achieving first place in the oncology original research session. The first place qualified […]

Our youngest members in the mentoring program “Jutronauci”

We are pleased to inform you that our young scientists – Agata Kozajda and Julia Świerczyńska have been qualified for the Mentoring Program “Jutronauci” under the patronage of Gazeta Wyborcza. For a year, they will develop their scientific skills and search for their dream career path under the supervision of Igor Kaczmarczyk, a PhD student […]

Decoding “metabolic memory” – how do glycemic control and variability affect epigenetic changes in young people with type 1 diabetes?

Type 1 diabetes (T1D) is the most common metabolic disease in childhood. It is caused by the destruction of pancreatic beta cells by one’s malfunctioning immune system. The lost beta cells are responsible for the production of insulin – an essential hormone in blood glucose levels regulation. Treatment of T1D demands life-long subcutaneous insulin supplementation […]

Screening for mobilization failure during hematopoietic stem cell transplantation through non-coding RNA profiling.

Transplantation of hematopoietic stem cells from bone marrow is a widely used method for treating various diseases, such as blood cancers, metabolic disorders, and autoimmune diseases. However, some patients are unable to undergo this procedure effectively due to problems with mobilizing an adequate number of stem cells. The study proposes to evaluate the role of […]

The role of proinsulin C-peptide and G-protein coupled receptor 146 (GPR146) – clinical observation of their signaling pathway’s impact on molecular pathways involved in diabetes-related complications.

The project aims to investigate the role of proinsulin C-peptide and G-protein coupled receptor 146 (GPR146) in type 2 diabetes mellitus (T2DM) complications. C-peptide is a short peptide that influences multiple cellular pathways, and its role in diabetes complications has become increasingly evident. The study postulates that C-peptide interacts with the GPR146 receptor, which may […]

Our new paper in Lancet Oncology!

We are pleased to inform about the success of our Ph.D. student Damian Mikulski, M.D. – the results of the ATLAS clinical trial (PMC006) in which he participated were published in the Lancet Oncology (IF 54.433) in the manuscript “Carfilzomib, lenalidomide, and dexamethasone or lenalidomide alone as maintenance therapy after autologous stem-cell transplantation in patients […]

Intrinsic tumour radiosensitivity as a marker of chemoradiotherapy-induced immunogenic effects in rectal cancer

Colorectal cancer (CRC) is the second leading cause of cancer death in the world. Standard treatment of patients with locally advanced cancer of the rectum includes chemoradiotherapy (CHRT) before surgery. In recent years, the new standard of treatment for some patients with CRC has become immunotherapy with the use of so-called immune checkpoint inhibitors (ICI) […]

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